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Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage

โœ Scribed by Dr. Marinos C. Dalakas; Marta E. Leon-Monzon; Isa Bernardini; William A. Gahl; Cheryl A. Jay


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
736 KB
Volume
35
Category
Article
ISSN
0364-5134

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โœฆ Synopsis


linked to the phenotype in the families we have analyzed (manuscript in preparation). These observations may indicate that convulsions could be only one of the modes of expression of BFNC and BIFC mutant genes.


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## Abstract Increased plasma levels of free fatty acids (FFA) occur in states of insulin resistance such as obesity and type 2 __diabetes mellitus__. These high levels of plasma FFA are proposed to play an important role for the development of insulin resistance but the mechanisms involved are stil