Z-Stereoselective Wittig olefination of 2-oxygenated cyclohexanones
β Scribed by Koreeda, Masato; Patel, Paresh D.; Brown, Lindsey
- Book ID
- 127211390
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 425 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Asymmetric Wittig-type olefination of 4-substituted cyclohexanones with chiral ligand-modified stable arsonium ylides has been examined. The 8-phenylmentholderived chiral arsonium ylide of 4 reacted with prochiral ketones 9a-d at -15Β°C to give the 4-substituted cyclohexylideneacetates lla--d in 58-6
The rhodium(I)-catalysed sequential silylformylation/Wittig olefination of terminal alkynes with hydrosilanes and carbon monoxide in the presence of stabilised P-ylides leads to substituted 2,4-dienoic esters in a one-pot procedure. The