( Z )-4-Chloro- N -(1-{2-[3-(4-chlorobenzoyl)ureido]ethyl}imidazolidin-2-ylidene)benzamide
✍ Scribed by Adan, Dalina; Sapari, Suhaila; Halim, Siti Nadiah; Yamin, Bohari M.
- Book ID
- 124154044
- Publisher
- International Union of Crystallography
- Year
- 2012
- Tongue
- English
- Weight
- 460 KB
- Volume
- 68
- Category
- Article
- ISSN
- 1600-5368
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📜 SIMILAR VOLUMES
The title compound, C~23~H~19~ClN~2~O~2~, has been obtained by the reaction of (__Z__)-4-(4-chlorobenzylidene)-2-phenyloxazol-5(4__H__)-one and benzylamide. The molecules are connected by two N—H...O intermolecular hydrogen bonds to form helicoidal chains running parallel to the __c__ axis.
## Abstract RPCNU was labelled with ^14^C on three positions: ‐ On the carboxyl of the acetyl groups ‐ On the carboxyl of the acetyl groups ‐ On the urea carbonyl
## Abstract The title compound (1) was synthesized by a 7‐step sequence. 4‐Amino‐2‐hydroxy‐[carbonyl‐^14^C]benzoic acid (1) was selectively methylated to provide the ether ester 2, which was smoothly chlorinated in acetic acid to give 3. The ester was hydrolyzed with aqueous potassium hydroxide to