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Youden test application in robustness assays during method validation

✍ Scribed by Karageorgou, Eftichia; Samanidou, Victoria


Book ID
121722519
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
612 KB
Volume
1353
Category
Article
ISSN
1873-3778

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Validation of a simple HPLC method for a
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## Abstract A simple HPLC method with ultraviolet detection has been developed and validated for the simultaneous determination of haplamine and its metabolites (__trans__/__cis__‐3,4‐dihydroxyhaplamine) in rat. A liquid–liquid extraction was used to extract the compounds from rat plasma. The analy