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Y(OTf)3-catalyzed novel Mannich reaction of N-alkoxycarbonylpyrroles, formaldehyde and primary amine hydrochlorides

✍ Scribed by Chuanxin Zhang; Jingchao Dong; Tieming Cheng; Runtao Li

Book ID: 104211529
Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 64 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)01985-7

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✦ Synopsis

A novel Mannich reaction between N-alkoxycarbonylpyrroles, formaldehyde and primary amine hydrochlorides is catalyzed by Y(OTf) 3 to afford a monoaminoalkylation product in good yield in aqueous media.

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