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YMDD motif mutations in chronic hepatitis B antiviral treatment naïve patients: a multi-center study

✍ Scribed by Tan, You-Wen; Ge, Guo-Hong; Zhao, Wei; Gan, Jian-He; Zhao, Yun; Niu, Zhi-Lin; Zhang, Dong-Jun; Chen, Li; Yu, Xue- Jun; Yang, Li-Jun

Book ID
121889065
Publisher
SciELO
Year
2012
Tongue
English
Weight
859 KB
Volume
16
Category
Article
ISSN
1413-8670

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## Abstract Although the rate at which mutations in the tyrosine‐methionine‐aspartate‐aspartate (YMDD) motif of hepatitis B virus polymerase form is high during prolonged lamivudine (LAM) therapy, these mutations sometimes occur naturally in treatment‐naïve patients with chronic hepatitis B. The pr