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Yeast Model System for Study of Mammalian Phosphodiesterases

✍ Scribed by Josephine M. Atienza; John Colicelli


Book ID
115638857
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
282 KB
Volume
14
Category
Article
ISSN
1046-2023

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Small peptides initiate sexual conjugation in the yeast Saccharomyces cerevisiae and this phenomenon is an ideal paradigm for studying the mode of action of mammalian peptide hormones. 'H-nmr spectroscopy was used to examine the conformation of linear and cyclic analogues of the a-factor (WHWLQLKPGQ