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Yeast expression of CYP2D6 at the plasma membrane is not the product of an endoluminal form

✍ Scribed by J. Loeper; D. Pompon


Book ID
118568849
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
128 KB
Volume
28
Category
Article
ISSN
0168-8278

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The purpose of this study was to clarify the pharmacokinetics of CYP2D6 substrates in female DA and Wistar rats, which are regarded as animal models of poor metabolizers and extensive metabolizers, respectively. In vivo pharmacokinetic and in vitro metabolic studies were conducted using metoprolol a