YBX1 expression and function in early hematopoiesis and leukemic cells
β Scribed by Jasjeet Bhullar; Vincent E. Sollars
- Book ID
- 105948114
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 839 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
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Cell differentiation and four WT1 isoforms were assessed in CD34(+) cells from patients with acute myelogenous leukemia in presence or absence of recombinant human GM-CSF and G-CSF, on days 0, 10 and 20 of culture. We found that WT1 isoforms expression was consistently higher in AML-derived CD34+ ce
## Abstract ## Background Patients with acute myeloid leukemia (AML) often obtain complete remission with chemotherapy but the majority of patients relapse. Combining chemotherapy and gene therapy appears to be a promising approach; however, the effects of chemotherapy on transgene expression in l