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Yb-DTPA, a novel contrast agent in magnetic resonance imaging: Application to rat kidney

✍ Scribed by Susanta K. Sarkar; Robert E. Rycyna; Robert E. Lenkinski; Henk A. Solleveld; Lewis B. Kinter

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
453 KB
Volume
17
Category
Article
ISSN
0740-3194

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✦ Synopsis

We have developed a novel contrast agent, ytterbium-diethylenetriamine pentaacetic acid (Yb-DTPA), for magnetic resonance imaging (MRI) and its mechanism of action is predominantly by the susceptibility mechanism. We have applied this contrast agent for renal MRI studies. We also demonstrate that Yb-DTPA has a renal clearance similar to that of inulin in rats and may therefore be useful for the estimation of glomerular filtration rate.

πŸ“œ SIMILAR VOLUMES

Local delivery of magnetic resonance (MR
Local delivery of magnetic resonance (MR) contrast agent in kidney using thermosensitive liposomes and MR imaging-guided local hyperthermia: A feasibility study in vivo
✍ Rares Salomir; Jean PalussiΓ¨re; Sigrid L. Fossheim; Astri Rogstad; Unni N. Wigge πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 485 KB

## Abstract ## Purpose To investigate the feasibility of local delivery of a magnetic resonance (MR) contrast agent in vivo using paramagnetic thermosensitive liposomes and infrared (IR) laser‐induced local hyperthermia under real‐time MR thermometry on rabbit kidney. ## Materials and Methods Re