✦ LIBER ✦
Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorumMarenzeller
✍ Scribed by Li-Gong Yao; Hai-Yan Zhang; Lin-Fu Liang; Xian-Jun Guo; Shui-Chun Mao; Yue-Wei Guo
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- German
- Weight
- 172 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Two new cembranoids, yalongenes A (1) and B (2), were isolated from the South China Sea soft coral Sarcophyton trocheliophorum Marenzeller. Their structures were elucidated by detailed spectroscopic analysis (IR, MS, and NMR) and by comparison with a related model compound. Yalongenes 1 and 2 were evaluated for their cytoprotective effects on SH‐SY5Y cell injury induced by H~2~O~2~ in vitro, and the result showed that only compound 1 had a significant cytoprotective activity at the concentration of 1 μM.