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Y chromosome microdeletions in Mexican males of couples with idiopathic recurrent pregnancy loss

✍ Scribed by Raul E. Piña-Aguilar; Sandra G. Martínez-Garza; Graciela Kohls; Marco A. Vargas-Maciel; Luis G. Vázquez de Lara; Claudia González-Ortega; Patricia Cancino-Villarreal; Antonio M. Gutiérrez-Gutiérrez

Book ID
115183876
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
113 KB
Volume
38
Category
Article
ISSN
1341-8076

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Microdeletions in interval 6 of the Y ch
Microdeletions in interval 6 of the Y chromosome of males with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene
✍ P. Vogt; A. C. Chandley; T. B. Hargreave; R. Keil; K. Ma; A. Sharkey 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 814 KB

For males with idiopathic sterility, a molecular screen specific for small lesions (microdeletions) in interval 6 of the Y chromosome was set up using 29 Y-DNA probes. A "de novo" microdeletion in Y interval 6 was detected in 2 out of 19 "chromosomally normal" sterile males. The first microdeletion