Y chromosomal polysomy: A unique case of 49,XYYYY in amniotic fluid cells

Two years' prospective experience using

Two years' prospective experience using fluorescence in situ hybridization on uncultured amniotic fluid cells for rapid prenatal diagnosis of common chromosomal aneuploidies

✍ A. Morris; E. Boyd; S. Dhanjal; G. W. Lowther; D. A. Aitken; J. Young; A. L. Men 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB 👁 2 views

A probe was generated from the YAC clone 831B9 that was suitable for the prenatal detection of trisomy 21using fluorescence in situ hybridization (FISH). This probe was initially tested on a series of 650 unselected amniotic fluid samples prior to the karyotype being available. 630 were correctly id