Tandem nucleophilic substitution - 1,3 d
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Ronald Grigg; Jasothara Markandu
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Article
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1989
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Elsevier Science
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French
β 195 KB
Regiospecific nucleophilic substitution reactions involving attack of the nitrogen atom of oximes on epoxides are used to generate nitrones which are then trapped in 1,3-dipolar cycloaddition reactions. These tandem processes are shown to be flexible and to have wide synthetic scope for the construc