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XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck

✍ Scribed by Erich M Sturgis; Edward J Castillo; Lei Li; Susan A Eicher; Sara S Strom; Margaret R Spitz; Qingyi Wei


Book ID
114393850
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
76 KB
Volume
38
Category
Article
ISSN
1368-8375

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Glutathione-S-transferase polymorphisms
✍ Lie Cheng; Erich M. Sturgis; Susan A. Eicher; David Char; Margaret R. Spitz; Qin πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 106 KB πŸ‘ 2 views

Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and