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XLI.?Hexahydropyrimidine and its benzoyl derivatives

โœ Scribed by Titherley, Arthur Walsh; Branch, Gerald Eyre Kirkwood

Book ID
118042466
Publisher
The Royal Society of Chemistry
Year
1913
Tongue
English
Weight
751 KB
Volume
103
Category
Article
ISSN
0368-1645

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A series of trifluoromethylated hexahydropyrimidine and tetrahydropyrimidine derivatives were synthesized and their in vitro cytotoxic activities were determined in colon cancer cell line (COLO 320 HSR). Compounds 4f, 4g, 4k, 5, and 7 proved to be the most active in this series of compounds. They re