Xestospongienols A–L, Brominated Acetylenic Acids from the Chinese Marine Sponge Xestospongia testudinaria

✍ Scribed by Dong Liu; Jing Xu; Wei Jiang; Zhiwei Deng; Nicole J. de Voogd; Peter Proksch; Wenhan Lin

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: German
• Weight: 168 KB
• Volume: 94
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.201100015

✦ Synopsis

Abstract

Chemical examination of the Chinese marine sponge Xestospongia testudinaria resulted in the isolation and characterization of twelve new brominated acetylenic acids, namely xestospongienols A–L (1a–1d, 2a–2d, and 3a–3d), together with the known analog 4. The structures of xestospongienols A–L were determined on the basis of 1D‐ and 2D‐NMR, IR, and MS analysis in association with the modified Mosher method. The structural patterns are characteristic of brominated unbranched C~16~‐alkyl chains containing polyene and acetylene moieties.