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Xenopus tropicalis genetics identifies chromatoblast stem cell mutant

✍ Scribed by Timothy C. Grammer; Mustafa K. Khokha; Maura A. Lane; Richard M. Harland

Book ID
116975944
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
66 KB
Volume
295
Category
Article
ISSN
0012-1606

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## Abstract Summary: Mutant Ξ» integrases catalyze site‐specific recombination reactions inside mammalian cells. Here we demonstrate that the integrase system can be used to eliminate resistance marker genes from the genome of mouse embryonic stem cells. So‐called integrative and excisive recombinat