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Xenopus laevis sperm proteins, previously identified as surface proteins with egg coat binding capability, are indeed histone H4, histone H3, and sperm specific protein SP2

✍ Scribed by Bernardini, Giovanni ;Donne, Isabella Dalle ;Norreri, Sabrina ;Negri, Armando ;Milzani, Aldo


Book ID
102336408
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
471 KB
Volume
263
Category
Article
ISSN
0022-104X

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✦ Synopsis


Abstract

Recently, four Xenopus sperm proteins thought to be involved in binding to the egg envelope were identified (Lindsay and Hedrick, J. Exp. Zool., 245:286–293, '88). We have studied the three more abundant ones of apparent molecular weight of 14, 19, and 25 kd in SDS‐PAGE. We have shown that these proteins are indeed nuclear basic proteins: the 14 kd is the histone H4, the 19 kd is the histone H3, and the 25 kd is the sperm‐specific protein SP2. © 1992 Wiley‐Liss, Inc.