𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Xenobiotic Response in Humanized Double Transgenic Mice Expressing Tetracycline-Controlled Transactivator and Human CYP1B1

✍ Scribed by Dae Y. Hwang; Kab R. Chae; Dong H. Shin; Jin H. Hwang; Chae H. Lim; Yeun J. Kim; Bum J. Kim; Jun S. Goo; Yun Y. Shin; In S. Jang; Jung S. Cho; Yong K. Kim

Book ID
115568938
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
393 KB
Volume
395
Category
Article
ISSN
0003-9861

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Enhanced skin carcinogenesis and lack of
Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)
✍ Paola Rojas; Fernando Benavides; Jorge Blando; Carlos Perez; Kim Cardenas; Ellen πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 221 KB

## Abstract Cyclin D1b is an alternative transcript of the cyclin D1 gene (__CCND1__) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870). Epidemiological studies have shown a correlation between the presence of t

The liver X-receptor alpha controls hepa
The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice
✍ MΓ©lanie Verreault; Kathy Senekeo-Effenberger; Jocelyn Trottier; Jessica A. Bonzo πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 741 KB

Glucuronidation, an important bile acid detoxification pathway, is catalyzed by enzymes belonging to the UDP-glucuronosyltransferase (UGT) family. Among UGT enzymes, UGT1A3 is considered the major human enzyme for the hepatic C24-glucuronidation of the primary chenodeoxycholic (CDCA) and secondary l