Xbra3 Induces Mesoderm and Neural Tissue in Xenopus laevis
โ Scribed by C.F. Strong; M.W. Barnett; D. Hartman; E.A. Jones; D. Stott
- Book ID
- 115598444
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 660 KB
- Volume
- 222
- Category
- Article
- ISSN
- 0012-1606
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In Xenopus, as in all amphibians and possibly in vertebrate embryos in general, mesoderm formation and the establishment of the dorsoventral axis depend on inductive cell interactions. Molecules involved in mesoderm induction include FGF which acts predominantly as a ventrolateral inducer, the TGF-P
During development of the Xenopus embryo, the formation of the nervous system depends on an inductive interaction between mesoderm and ectoderm. The result is a neural tube that is regionally differentiated along the anterior-posterior axis from forebrain to spinal cord (Fig. 1). The discovery of ge