X;autosome translocations in females with Duchenne or Becker muscular dystrophy (reply)
β Scribed by WORTON, R. G.
- Book ID
- 109744337
- Publisher
- Nature Publishing Group
- Year
- 1986
- Tongue
- English
- Weight
- 105 KB
- Volume
- 322
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/322292a0
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There are rare female patients who suffer from Duchenne or Becker muscular dystrophy because they carry an X;autosome translocation with a breakpoint in the dystrophin gene. We have defined the positions of seven of these breakpoints with respect to exon-containing HindIII fragments detected by dyst
The existence of linkage has been investigated between the Xg blood group system, two DNA restriction fragment length polymorphisms (RFLPs) located on the short arm of the X chromosome, Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). No linkage was found between the Xg locus a