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X;autosome translocations in females with Duchenne or Becker muscular dystrophy (reply)

✍ Scribed by WORTON, R. G.


Book ID
109744337
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
105 KB
Volume
322
Category
Article
ISSN
0028-0836

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There are rare female patients who suffer from Duchenne or Becker muscular dystrophy because they carry an X;autosome translocation with a breakpoint in the dystrophin gene. We have defined the positions of seven of these breakpoints with respect to exon-containing HindIII fragments detected by dyst

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The existence of linkage has been investigated between the Xg blood group system, two DNA restriction fragment length polymorphisms (RFLPs) located on the short arm of the X chromosome, Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). No linkage was found between the Xg locus a