Xanthine nucleotide-specific G-protein α-subunits: a novel approach for the analysis of G-protein-mediated signal transduction

Application of surface plasmon resonance

Application of surface plasmon resonance for analysis of protein–protein interactions in the G protein-mediated signal transduction pathway

✍ Vladlen Z. Slepak 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 2 views

Hundreds of extracellular stimuli are received by cells via the pathways consisting of three basic components: cell-surface receptors, heterotrimeric G proteins, and intracellular effector enzymes or ion channels. A number of additional molecules, including G protein-coupled receptor kinases (GRKs),