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Xanomeline: A potent and selective M1 muscarinic agonist in vitro

โœ Scribed by Mitch, CH; Bymaster, FP; Calligaro, DO; Quimby, SJ; Sawyer, BD; Shannon, HE; Ward, JS; Olesen, PH; Sauerberg, P; Sheardown, MJ; Suzdak, PD


Book ID
124132500
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
173 KB
Volume
15
Category
Article
ISSN
0197-4580

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Xanomeline: A selective muscarinic agoni
โœ Frank P. Bymaster; Celia A. Whitesitt; Harlan E. Shannon; Neil DeLapp; John S. W ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 147 KB ๐Ÿ‘ 3 views

Xanomeline is a novel muscarinic receptor agonist relatively devoid of parasympathomimetic side effects. Xanomeline had high affinity for muscarinic receptors and much lower affinity for a variety of other neuronal receptors in radioligand binding assays. Functional studies in cell lines transfected