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X-ray studies of the binding of small anionic inhibitors at the carboxypeptidase A active site.

✍ Scribed by S. Mangani; P. Carloni; P. Oriole

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
82 KB
Volume
43
Category
Article
ISSN
0162-0134

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New peptide and ester substrate analogues for carboxypeptidase A have been prepared which differ by the possession of an acylcyanamide residue of comparable acidity in place of the C-terminal carboxylic acid group that is normally required by the enzyme. The surrogates are cleaved respectively \(2 \