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X-ray diffraction study of the interaction of the amino terminal half-molecule of histone H4 with duplex DNA

✍ Scribed by E. J. Wachtel; R. Sperling


Publisher
Wiley (John Wiley & Sons)
Year
1983
Tongue
English
Weight
391 KB
Volume
22
Category
Article
ISSN
0006-3525

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✦ Synopsis


The interaction of the amino terminal half-molecule of histone H4 with duplex DNA has been studied by fiber x-ray diffraction. Changes induced in the diffraction pattern of B-DNA by the presence of the bound peptide have been Fourier-analyzed and the results presented in terms of a deweighted radial projection of the electron density. We conclude that the peptide binds on the major groove side of the sugar-phosphate chain.

H i o c h m . 75,379-389.