Cephalin readily combines with basic proteins, such as histones, forming a precipitate which may be insoluble in water and organic solvents (Chargaff, '38; Chargaff and Ziff, '39). From the combining ratios it was shown that cephalin, which is acidic, combines with basic proteins through salt linkag
X-ray diffraction studies of lipide emulsions
β Scribed by Palmer, Kenneth J. ;Schmitt, Francis O.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1941
- Tongue
- English
- Weight
- 567 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0095-9898
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β¦ Synopsis
In a preceding paper were reported the results of an x-ray investigation of the dimensions and configurations of certain nerve lipides both in the wet and dry condition (Bear, Palmer arid Schmitt, '41). Particularly striking was the fact that, in the case of lipide mixtures, although the individual components form separate phases in the dry condition, a single phase is formed when the mixture is emulsified with water. Moreover, if cephalin is contained in the mixture, wetting produces considerable increase in the identity period. I n the present paper are described the results of a more detailed study of such lipide emulsions undertaken not only to obtain information concerning the lipide molecules themselves but as an aid in interpreting the diffraction patterns of medullated nerves. Of particular importance in the latter connection is the question as to whether the lipides, such as occur in the myelin sheath, when associated with water to the extent obtaining in the sheath, can give rise to diffraction patterns similar to those of fresh nerves. This question is discussed in some detail in the following paper (Schmitt, Bear and Palmer, '41).
EXPER.IMENTAL RESULTS
π SIMILAR VOLUMES
Since lipide molecules enter prominently into the structure of many protoplasmic constituents (for reviews see Schmidt, '37 ; Schmitt, '39) it is desirable to understand the way in which these molecules pack in oriented layers, their approximate dimensions and configurations, and the effect of the c