X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity

✍ Scribed by Christian Lerner; Armin Ruf; Volker Gramlich; Birgit Masjost; Gerhard Zürcher; Roland Jakob-Roetne; Edilio Borroni; François Diederich

• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 122 KB
• Volume: 40
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/1521-3773(20011105)40:21<4040::aid-anie4040>3.0.co;2-c