Syntheses and resolutions of new chiral
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Yuxue Liang; Shuang Gao; Huihui Wan; Junwei Wang; Huilin Chen; Zhuo Zheng; Xinqu
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Article
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2003
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Elsevier Science
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English
⚖ 241 KB
The new chiral backbones (R)-(+)-and S-(-)-2-amino-2%-hydroxy-6,6%-dimethyl-1,1%-biphenyl and (R)-(+)-and (S)-(-)-2-amino-2%-hydroxy-4,4%,6,6%-tetramethyl-1,1%-biphenyl were synthesized from o-methylaniline and 2,4-dimethyl-aniline respectively in seven steps. A new resolution method was developed t