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X-ray crystal optics based on the Bragg-Fresnel scattering

✍ Scribed by F.N Chukhovskii; W.Z Chang; E Förster


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
351 KB
Volume
124
Category
Article
ISSN
0030-4018

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## Abstract A new class of nonpeptidic inhibitors of the Zn^II^‐dependent metalloprotease neprilysin with __IC__~50~ values in the nanomolar activity range (0.034–0.30 μM) were developed based on structure‐based __de novo__ design (__Figs. 1__ and __2__). The inhibitors feature benzimidazole and im