Stereochemical Study of a Bradicardisant
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Delphine Duval; Philippe Hennig; Jean Paul Bouchet; Joel Vian; Jean Louis Peglio
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Article
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1997
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John Wiley and Sons
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English
β 387 KB
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A chiral bradicardisant benzazepine-type drug with an asymmetric carbon and a tertiary amino nitrogen was studied as the chloride salt. X-ray analysis in the solid state of the salt formed upon protonation of the base shows the occurrence in the unit cell of two diastereomeric species with horseshoe