Striated (Str) and bare patches (Bpa) are X-irradiation-induced, X-linked dominant mouse mutations that are lethal prenatally in hemizygous males. To map the Str mutation, we generated a backcross involving Mus castaneus. Pedigree analysis of 193 affected female and normal male progeny from the cr
โฆ LIBER โฆ
X-linked nonprogressive congenital cerebellar hypoplasia: Clinical description and mapping to chromosome Xq
โ Scribed by Dr. Sergei N. Illarioshkin; Hajime Tanaka; Shoji Tsuji; Elena D. Markova; Natalya N. Nikolskay; Irina A. Ivanova-Samolenskay
- Book ID
- 102709241
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 819 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0364-5134
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Families with mentally retarded males found to be negative for FRAXA and FRAXE mutations are useful in understanding the genetic basis of X-linked mental retardation. According to the most recent data (updated to 1999), 69 MRX loci have been mapped and 6 genes cloned. Here we report on a linkage stu