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X-linked laterality sequence: Situs inversus, complex cardiac defects, splenic defects

✍ Scribed by Mathias, Robert S. ;Lacro, Ronald V. ;Jones, Kenneth Lyons ;Opitz, John M. ;Reynolds, James F.


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
346 KB
Volume
28
Category
Article
ISSN
0148-7299

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✦ Synopsis


The association of abdominal situs inversus, complex cardiac defects, and alterations in development of the spleen represents a developmental field complex with variable expression of altered laterality. Familial and inherited cases documenting respectively autosomal recessive and dominant inheritance have been reported. We report on the first family in which X-linked recessive inheritance of this defect has been documented.