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X-inactivation analysis in the 1990s: promise and potential problems

✍ Scribed by Busque, L; Gilliland, D G


Book ID
110053765
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
90 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract Autism spectrum disorders (ASD) are complex genetic disorders more frequently observed in males. Skewed X chromosome inactivation (XCI) is observed in heterozygous females carrying gene mutations involved in several X‐linked syndromes. In this study, we aimed to estimate the role of X‐l