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X-chromosome inactivation may explain the difference in viability of XO humans and mice

✍ Scribed by Ashworth, Alan; Rastan, Sohaila; Lovell-Badge, Robin; Kay, Graham


Book ID
109777147
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
492 KB
Volume
351
Category
Article
ISSN
0028-0836

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## Abstract In this paper, we hypothesize that X chromosome‐associated mechanisms, which affect X‐linked genes and are behind the immunological advantage of females, may also affect X‐linked microRNAs. The human X chromosome contains 10% of all microRNAs detected so far in the human genome. Althoug