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X and Y chromosome loss as sole abnormality in acute non-lymphocytic leukemia (ANLL)

✍ Scribed by Carolyn B. Riske; Rodman Morgan; Sharon Ondreyco; Avery A. Sandberg


Book ID
119106129
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
365 KB
Volume
72
Category
Article
ISSN
0165-4608

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Acute promyelocytic leukemia (APL) is characterized by the presence of a chromosomal rearrangement involving retinoic acid receptor alpha (RARalpha) gene generating the X-RARalpha fusion. We describe here a unique RARalpha gene rearrangement in a patient with M3r subtype of APL. Conventional cytogen