Wurster coated aspirin II. An In vitro and In vivo correlation of rate from sustained-release preparations

Development of a respirable, sustained r

Development of a respirable, sustained release microcarrier for 5-fluorouracil II: In vitro and in vivo optimization of lipid coated nanoparticles

✍ Cory J. Hitzman; William F. Elmquist; Timothy S. Wiedmann 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 1 views

The release rate of 5-fluorouracil (5-FU) from lipid-coated nanoparticles (LNPs) was determined to develop a respirable delivery system for use as adjuvant (postsurgery) therapy for lung cancer. LNPs were prepared by spray drying, and the in vitro release was measured by microdialysis. The compositi