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WT1 gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo-monocytic leukemia?

โœ Scribed by Peter Bader; Charlotte Niemeyer; Gerrit Weber; Tiziana Coliva; Vincenzo Rossi; Hermann Kreyenberg; Anja Gerecke; Andrea Biondi


Book ID
114792665
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
102 KB
Volume
73
Category
Article
ISSN
0902-4441

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Both WT1 and PRAME are highly expressed in acute myeloid leukemia (AML) patients. To assess the efficacy of their simultaneous detection for the purpose of monitoring minimal residual disease (MRD), we used real-time quantitative RT-PCR to quantify both WT1 and PRAME transcript levels in the bone ma