Expression of T-cell receptors of gammddelta type characterizes a small subset of peripheral T lymphocytes which is homogeneously composed of cytolytic cells and, in most instances, lack CD4 and CD8 differentiation antigens. By the use of anti-TCR gammddelta MAbs it is possible to identify two disti
WSA 13 - Gamma-Delta T Cells and NKT Cells
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 109 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0014-2980
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β¦ Synopsis
Abstract
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## Abstract Activated NKT cells produce cytokines such as ILβ4 and IFNβΞ³ that function locally to influence the strength and functional development of antigenβspecific T cells. Here we identify an alternative mechanism by which NKT cells influence the strength of T cell responses: through modulatio