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WS15.1 Development of a human model of airway epithelial cells invalidated for CFTR

โœ Scribed by Bellec, J.; Losa, D.; Bacchetta, M.; Nguyen, T.H.; Chanson, M.

Book ID
122559302
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
67 KB
Volume
12
Category
Article
ISSN
1569-1993

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๐Ÿ“œ SIMILAR VOLUMES

Gene targeting of a CFTR allele in HT29
Gene targeting of a CFTR allele in HT29 human epithelial cells
โœ Chahrzad Montrose-Rafizadeh; Jolanta Kole; L. Michele Bartkowski; Linda H. Lee; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 242 KB

HT29 cells endogenously express the cystic fibrosis transmembrane conductance regulator (CFTR) and have been used previously as a model to examine cellular regulation of CFTR expression and chloride secretory function. Homologous recombination has been used to specifically disrupt CFTR transcription