𝔖 Bobbio Scriptorium
✦   LIBER   ✦

WR-2721 (WR): A potent hypocalcemic agent and inhibitor of parathyroid hormone secretion

✍ Scribed by D. Glover; S. Goldfarb; J.H. Glick


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
172 KB
Volume
10
Category
Article
ISSN
0360-3016

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Isolation and identification of 1α-hydro
✍ Alex J. Brown; Cynthia S. Ritter; A.S. Weiskopf; P. Vouros; Gino J. Sasso; Milan 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB

## Abstract Since our original demonstration of the metabolism of 1α,25(OH)~2~D~3~ into 1α,25(OH)~2~‐3‐epi‐D~3~ in human keratinocytes, there have been several reports indicating that epimerization of the 3 hydroxyl group of vitamin D compounds is a common metabolic process. Recent studies reported

1α,25-Dihydroxy-3-Epi-vitamin D3, a natu
✍ A.J. Brown; C. Ritter; E. Slatopolsky; K.R. Muralidharan; W.H. Okamura; G.S. Red 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 1 views

1␣,25(OH) 2 D 3 is an important negative regulator of parathyroid hormone (PTH) gene transcription. In parathyroid cells, as in other target tissues, 1␣,25(OH) 2 D 3 is degraded by side chain oxidation by the inducible 24-hydroxylase. We have previously shown that one metabolite of this pathway, 1␣,