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Worse Prognosis with Gene Mutations of Beta-myosin Heavy Chain than Myosin-Binding Protein C in Chinese Patients with Hypertrophic Cardiomyopathy

โœ Scribed by Rutai Hui; Shuxia Wang; Yubao Zou; Chunyan Fu; Xiqi Xu; Jizheng Wang; Lei Song; Hu Wang; Jingzhou Chen; Jianwei Wang; Tujun Huan


Book ID
112060706
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
131 KB
Volume
31
Category
Article
ISSN
0160-9289

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Unexpectedly low mutation rates in beta-
โœ Roberta Roncarati; Michael V.G. Latronico; Beatrice Musumeci; Stefania Aurino; A ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 138 KB

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease. Fourteen sarcomeric and sarcomere-related genes have been implicated in HCM etiology, those encoding ฮฒ-myosin heavy chain (__MYH7__) and cardiac myosin binding protein C (__MYBPC3__) reported as the most frequently mutated