Work flow methodology: A proposed approach for analysis and conceptual design of large scale computer based information systems

High throughput flow cytometry based yea

High throughput flow cytometry based yeast two-hybrid array approach for large-scale analysis of protein-protein interactions

✍ Jun Chen; Mark B. Carter; Bruce S. Edwards; Hong Cai; Larry A. Sklar 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 733 KB

## Abstract The analysis of protein‐protein interactions is a key focus of proteomics efforts. The yeast two‐hybrid system (Y2H) has been the most commonly used method in genome‐wide searches for protein interaction partners. However, the throughput of the current yeast two‐hybrid array approach is