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Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity

✍ Scribed by Hua Zi Piao; In Young Choi; Jin-Sun Park; Hee-Sun Kim; Jae Hoon Cheong; Kun Ho Son; Su Jin Jeon; Kwang Ho Ko; Won-Ki Kim


Book ID
116576414
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
638 KB
Volume
8
Category
Article
ISSN
1567-5769

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## Abstract 15‐Lipoxygenase‐1 (15‐LOX‐1) is an enzyme of the inflammatory eicosanoid pathway whose expression is known to be lost in colorectal cancer (CRC). We have previously shown that reintroduction of the gene in CRC cell lines slows proliferation and induces apoptosis (Cimen et al. [2009] Can