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Wnt/β-Catenin Signaling Pathway Upregulates c-Myc Expression to Promote Cell Proliferation of P19 Teratocarcinoma Cells

✍ Scribed by Shuai Zhang; Yi Li; Yuling Wu; Kun Shi; Lujun Bing; Jing Hao


Book ID
115550420
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
832 KB
Volume
295
Category
Article
ISSN
1932-8486

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## Abstract Overexpression of cyclooxygenase‐2 (COX‐2) and elevation of its derivative prostaglandin E~2~ (PGE~2~) are implicated in human esophageal squamous cell carcinoma. The expression of c‐Myc, an oncogenic transcription factor, is also upregulated in this malignant disease. This study sought