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WNTs modulate cell fate and behavior during vertebrate development

✍ Scribed by Randall T. Moon; Jeffrey D. Brown; Monica Torres


Book ID
114173734
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
544 KB
Volume
13
Category
Article
ISSN
0168-9525

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Wnt signaling regulates many aspects of vertebrate development and adult stem cells. Deregulation of Wnt signaling causes development defect and cancer. The signaling is categorized in two pathways: canonical and noncanonical. Both pathways are initiated by Wnt ligands and Frizzled receptors. Canoni