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Wnt5a promotes migration of human osteosarcoma cells by triggering a phosphatidylinositol-3 kinase/Akt signals

✍ Scribed by Zhang, Ailiang; He, Shuanghua; Sun, Xiaoliang; Ding, Lianghua; Bao, Xinnan; Wang, Neng


Book ID
125400441
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
828 KB
Volume
14
Category
Article
ISSN
1475-2867

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## Abstract In __de novo__ glioblastoma multiforme, loss of the tumour suppressor protein PTEN can coincide with the expression of a naturally occurring mutant epidermal growth factor receptor known as Ξ”EGFR. Ξ”EGFR signals constitutively via the phosphatidylinositol 3‐kinase (PI3K)/protein kinase A