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Withdrawal from ingested diazepam produces a pentylenetetrazol-like stimulus in rats

โœ Scribed by Cynthia M. Harris; Smart O. Idemudia; Daniel Benjamin; Samiran Bhadra; Harbans Lal

Book ID
102141940
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
370 KB
Volume
12
Category
Article
ISSN
0272-4391

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In the present experiment, rats were trained to discriminate the stimulus properties of an anxiogenic drug, pentylenetetrazol (PTZ), 20 mgikg, from saline using a food-rewarded two-lever choice task. Following training: substitution tests were performed, and rats selected the PTZ-appropriate lever a