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Withanolides from Physalis alkekengi var. francheti

✍ Scribed by Yi-Zheng Li; Ying-Ming Pan; Xiao-Yan Huang; Heng-Shan Wang

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
258 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two new withanolides, namely (20__S__,22__R__)‐15__α__‐acetoxy‐5__α__‐chloro‐6__β__,14__β__‐dihydroxy‐1‐oxowitha‐2,24‐dienolide (1) and (22__R__)‐5__β__,6__β__ : 14__α__,17 : 14__β__,26‐triepoxy‐2__α__‐ethoxy‐13,20,22‐trihydroxy‐1,15‐dioxo‐16__α__,24‐cyclo‐13,14‐secoergosta‐18,27‐dioic acid 18→20,27→22‐dilactone (2), along with six known compounds, physagulin B (3), withangulatin A (4), physalin I (5), withaminimin (6), physagulin J (7), and ergosta‐5,25‐diene‐3__β__,24__ξ__‐diol (8), were isolated from the whole plant of Physalis alkekengi var. francheti. Their structures were elucidated on the basis of spectroscopic analyses.

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