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Withaferin A inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules by inactivation of Akt and NF-κB in human pulmonary epithelial cells

✍ Scribed by Jung Hwa Oh; Taeg Kyu Kwon


Book ID
116576515
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
713 KB
Volume
9
Category
Article
ISSN
1567-5769

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f